I've been very, very busy getting shops up and running on Etsy, 1000markets, Imagekind, and Cafepress. Each has a focus, and I have work left to do on all.
Etsy has many handmade items. I'm not sure how well original art sells there.
1000markets is a great place for original art. Let's hope buyers find me!
Imagekind is a great place to buy prints, framed or not.
And, Cafepress is really good for "stuff" - t-shirts, cards, etc. - and only has the beginnings of a Fiona shop so far.
Check out "other places you'll find me" to the right for each!